Thursday, April 5, 2012

Connections to Past Knowledge - Part II

Last semester in Biology 413 we were introduced to DNA/RNA transcription/translation. We have been covering it in this class since the return from spring break, but in considerably greater detail. Probably the most striking aspect of this, at least to me, is the level of detail we've seen it in. I understand that the detail is necessary to understand how it works, but I didn't realize there was as much to it as there is.

I'll use the following as an example: in Biology 413 the difference between prokaryotic and eukaryotic transcription and translation was mentioned in passing but never really discussed. In this course it is, and the amount of material is considerable. I had never heard of a Pribnow Box until one week ago. Now I know that it is one of the elements that makes up promoter structure in the process of synthesizing RNA. It is 10 boxes upstream from the TSS, or transcription start site, and is the first promoter element in the transcription process.

I know there is much more. And I have no doubt we will see more before this semester ends.

2 comments:

  1. It's interesting that you mention the pribnow box. Many of the components of these cellular processes are familiar from genetics, even if I didn't understand it in great detail. I felt the same way about the pribnow box - its nice to learn about something new!

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  2. As I haven't had Genetics, I had no idea what a Pribnow box was. So at least when I come across a discussion about how a particular condition is manifested genetically, I will have a better idea what this part of the process is and how it fits. It may not (ever) be mentioned specifically, but at least it gives me an idea in what direction to think in.

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